Kids First https://validator.w3.org/feed/docs/rss2.html Genomic Insights into the Biology of T-lineage Acute Lymphoblastic Leukemia Germline Whole-Genome Sequencing in Early-Onset Pediatric Solid Tumors Implicates Novel Risk Factors A Bayesian-Based Integrative Bioinformatics Analysis Nominates Oncogenic Drivers in Neuroblastoma Microglia in diffuse midline glioma contribute to extracellular matrix remodelling and cancer cell invasion Clinical implications of RAS mutations in AML: prognostic significance is based upon the involved gene and mutation complexity The PLK4 inhibitor RP-1664 demonstrates potent efficacy in neuroblastoma preclinical models through a dual mechanism of sensitivity Systematic analysis of snRNA genes reveals frequent RNU2-2 variants in dominant and recessive developmental and epileptic encephalopathies Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states Differential expression of cancer-related genes supports prediction of poor response to first-line treatments in T-ALL pediatric patients with high minimal residual disease Gene expression dynamics of human and mouse craniofacial development at the single-cell level Aggregation of gene regulatory information and knowledge on FAIR principles enables discovery of pathogenic gene regulatory variants BCL11B enhancer hijacking by t(14;16)(q32;q24) translocation defines a novel high-risk subtype of T-ALL The CFDE Workbench: Integrating Metadata and Processed Data from Common Fund Programs Defining the Functional Role and Potential as an Immunotherapeutic Target of ALCAM in Neuroblastoma De novo mutations and environmental modifiers: lessons from neural tube defects Single vs Dual Genetic Disease in Children with Congenital Anomalies and Solid Tumors ASHG2026 The hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis Alternative splicing in pediatric central nervous system tumors highlights oncofetal candidate CLK1 exon 4 Grants Kids First DRC Study Demonstrates a New Standard for Pediatric Research Turner Lab Tools on CAVATICA Show What’s Possible with Kids First Data Personas for the translational workforce Data Lakes, Clouds, and Commons: A Review of Platforms for Analyzing and Sharing Genomic Data Role of repulsive guidance signaling and GPR180 in pediatric low-grade glioma infiltration A Framework for the Interoperability of Cloud Platforms: Towards FAIR Data in SAFE Environments Expanding the MOG phenotype: Brainstem encephalitis with punctate and curvilinear enhancement Home Studies Help Center Cost FAQs Data Security An evaluation of genetic predisposition to congenital anomalies and pediatric cancer supports KAT6B as a novel neuroblastoma susceptibility gene Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants FAT4 identified as a potential modifier of orofacial cleft laterality Integrative approaches generate insights into the architecture of non-syndromic cleft lip with or without cleft palate Publications EM-mosaic detects mosaic point mutations that contribute to congenital heart disease X-linked genetic associations in sporadic thoracic aortic dissection Synergistic Associations of PNPLA3 I148M Variant, Alcohol Intake, and Obesity With Risk of Cirrhosis, Hepatocellular Carcinoma, and Mortality Dexamethasone Suppresses Palatal Cell Proliferation through miR-130a-3p Maternal effect genes: Update and review of evidence for a link with birth defects muCNV: Genotyping Structural Variants for Population-level Sequencing From Questions to Action: A Parent’s Journey with Kids First Data MicroRNA-124-3p suppresses mouse lip mesenchymal cell proliferation through the regulation of genes associated with cleft lip in the mouse High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios What If Meerkat: An Algorithm to Reliably Identify Structural Variations and Predict Their Forming Mechanisms DMRscaler: a scale-aware method to identify regions of differential DNA methylation spanning basepair to multi-megabase features News