跳至主要内容
搜索

Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.

Background: Pediatric diffuse midline gliomas (DMGs) are incurable childhood cancers.
The imipridone ONC201 has shown early clinical efficacy in a subset of
DMGs. 然而, the anticancer mechanisms of ONC201 and its derivative
ONC206 have not been fully described in DMGs.

关闭菜单