NCI Cancer Research Data Commons: Lessons Learned and Future State.

More than ever, scientific progress in cancer research hinges on our
ability to combine datasets and extract meaningful interpretations to
better understand diseases and ultimately inform the development of better
treatments and diagnostic tools. To enable the successful sharing and use
of big data, the NCI developed the Cancer Research Data Commons (CRDC),
providing access to a large, comprehensive, and expanding collection of
cancer data. The CRDC is a cloud-based data science infrastructure that
eliminates the need for researchers to download and store large-scale
datasets by allowing them to perform analysis where data reside. Over the
past 10 年, the CRDC has made significant progress in providing access
to data and tools along with training and outreach to support the cancer
research community. In this review, we provide an overview of the history
and the impact of the CRDC to date, lessons learned, and future plans to
further promote data sharing, accessibility, 互操作性, and reuse.
See related articles by Brady et al., p. 1384, Wang et al., p. 1388, 和
Pot et al., p. 1396.