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Kids First Studies

Empower your research through Kids First data, tools and resources. Discover the robust collection of childhood cancer, congenital disorder, and cross-condition data available now.

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Cancer

Kids First: T-Cell ALL

NIH X01 Project Abstract - David Teachey, PI
Aligned Reads
Individual gVCFs
VCFs
Gene Expression TSVs
Latest Release
Apr 24, 2025
First Release
Nov 2, 2021
Cancer

Children’s Brain Tumor Network (CBTN)

CBTN Homepage
Aligned Reads
Individual gVCFs
Family-Based VCFs
Gene Expression TSVs
Annotated Somatic Mutations
Somatic Copy Number Variations
Latest Release
Oct 16, 2024
First Release
Jun 18, 2018
Congenital Disorder

Kids First: Cornelia de Lange Syndrome

NIH X01 Project Abstract - Ian Krantz, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Aug 2, 2024
First Release
Sep 12, 2022
Cancer

Kids First: Enchondromatoses

NIH X01 Project Abstract - Nara Sobreira, PI
Aligned Reads
Unaligned Reads
VCFs
Latest Release
Mar 19, 2024
First Release
Apr 10, 2020
Congenital Disorder

Kids First: Bladder extrophy, Epispadias, Complex

NIH X01 Project Abstract - Angie Jelin, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Mar 19, 2024
First Release
Oct 18, 2022
Cancer

Kids First: Ewing Sarcoma – Genetic Risk

NIH X01 Project Abstract - Joshua Schiffman, PI
Aligned Reads
Individual gVCFs
Latest Release
Feb 3, 2024
First Release
Jun 18, 2018
Congenital Disorder

Kids First: Chromosome 18 Structural Birth Defects

NIH X01 Project Abstract - Jannine De Mars Cody, PI
Aligned Reads
Individual gVCFs
Latest Release
Nov 29, 2023
First Release
Nov 29, 2023
Congenital Disorder

Kids First: Recessive Structural Brain Defects

NIH X01 Project Abstract - Joseph Gleeson, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Oct 23, 2023
First Release
Oct 23, 2023
Congenital Disorder

Kids First: Esophageal Atresia and Tracheoesophageal Fistulas

NIH X01 Project Abstract - Wendy Chung, PI
Aligned Reads
Latest Release
Aug 23, 2023
First Release
Aug 23, 2023
Cross Condition

Kids First: Leukemia & Heart Defects in Down Syndrome

NIH X01 Project Abstract - Philip Lupo and Stephanie Sherman, PIs
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Aug 11, 2023
First Release
Sep 28, 2021
Congenital Disorder

Kids First: Structural Defects of The Neural Tube

NIH X01 Project Abstract - Joseph Gleeson, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Aug 7, 2023
First Release
Aug 7, 2023
Congenital Disorder

Kids First: Kidney and Urinary Tract Defects

NIH X01 Project Abstract - Ali Gharavi, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Jul 17, 2023
First Release
Dec 2, 2020
Cancer

Kids First: Intracranial Germ Cell Tumors

NIH X01 Project Abstract - Ching Lau, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Jun 6, 2023
First Release
Jun 6, 2023
Congenital Disorder

Kids First: Fetal Alcohol Spectrum Disorders

NIH X01 Project Abstract - Christina Chambers, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
May 15, 2023
First Release
May 15, 2023
Congenital Disorder

Kids First: Orofacial Clefts – Philippines

NIH X01 Project Abstract - Elizabeth Leslie, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
May 9, 2023
First Release
May 9, 2023
Congenital Disorder

Kids First: CHARGE Syndrome

NIH X01 Project Abstract - Donna Martin, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Apr 27, 2023
First Release
Apr 27, 2023
Congenital Disorder

Kids First: Laterality Birth Defects

NIH X01 Project Abstract - Stephanie Ware, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Apr 12, 2023
First Release
Mar 12, 2023
Congenital Disorder

Kids First: Adolescent Idiopathic Scoliosis

NIH X01 Project Abstract - Jonathan Rios, PI
Aligned Reads
Individual gVCFs
Latest Release
Apr 6, 2023
First Release
Oct 12, 2018
Cancer

Kids First: Myeloid Malignancies

NIH X01 Project Abstract - Soheil Meshinchi, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Sep 23, 2021
First Release
Sep 23, 2021
Congenital Disorder

Kids First: Congenital Heart Defects

NIH X01 Project Abstract - Christine Seidman, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Sep 21, 2021
First Release
Jun 18, 2018
Congenital Disorder

Kids First: Microtia – Hispanic

NIH X01 Project Abstract - Jonathan Seidman, PI
Aligned Reads
Latest Release
Sep 3, 2021
First Release
Dec 17, 2020
Congenital Disorder

Kids First: Nonsyndromic Craniosynostosis

NIH X01 Project Abstract - Simeon Boyd, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Aug 23, 2021
First Release
Aug 23, 2021
Congenital Disorder

Kid First: Hemangiomas (PHACE)

NIH X01 Project Abstract - Dawn Siegel, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Aug 23, 2021
First Release
Aug 23, 2021
Cross Condition

Kids First: Intersections of Cancer & SBD

NIH X01 Project Abstract - Hakon Hakonarson, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Jun 10, 2021
First Release
Jun 10, 2021
Congenital Disorder

Kids First: Congenital Diaphragmatic Hernia

NIH X01 Project Abstract - Wendy Chung, PI
Aligned Reads
Individual gVCFs
Latest Release
May 15, 2021
First Release
Feb 18, 2018
Congenital Disorder

Kids First: Orofacial Cleft – European Ancestry

NIH X01 Project Abstract - Mary Marazita, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Apr 9, 2021
First Release
Jun 18, 2018
Congenital Disorder

Kids First: Craniofacial Microsomia

NIH X01 Project Abstract - Daniela Luquetti, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Nov 18, 2020
First Release
Nov 18, 2020
Cancer

Kids First: Osteosarcoma

NIH X01 Project Abstract - Kenan Onel, PI
Aligned Reads
Latest Release
Aug 24, 2020
First Release
Aug 24, 2020
Cancer

Kids First: Novel Cancer Susceptibility in Families (from BASIC3)

NIH X01 Project Abstract - Sharon Plon, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Unaligned Reads
Latest Release
Jul 21, 2020
First Release
Jul 21, 2020
Congenital Disorder

Kids First: Orofacial Cleft – African and Asian Ancestry

NIH X01 Project Abstract - Azeez Butali and Terri Beaty, PIs
Aligned Reads
Individual gVCFs
Latest Release
Jun 23, 2020
First Release
Jun 23, 2020
Cancer

Kids First: Familial Leukemia

NIH X01 Project Abstract - Charles Mullighan, PI
Aligned Reads
Unaligned Reads
VCFs
Latest Release
Jun 17, 2020
First Release
Jun 17, 2020
Cancer

Kids First: Neuroblastoma

NIH X01 Project Abstract - John Maris, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Unaligned Reads
Gene Expression TSVs
Latest Release
Sep 25, 2019
First Release
Sep 25, 2019
Congenital Disorder

Kids First: Orofacial Cleft – Latin American

NIH X01 Project Abstract - Mary Marazita, PI
Aligned Reads
Individual gVCFs
Family-Based VCFs
Latest Release
Jun 27, 2019
First Release
Jun 27, 2019
Congenital Disorder

Kids First: Disorders of Sex Development

NIH X01 Project Abstract - Eric Vilain, PI
Aligned Reads
Individual gVCFs
Latest Release
May 28, 2019
First Release
Mar 26, 2019
Congenital Disorder

Kids First: Syndromic Cranial Dysinnervation

NIH X01 Project Abstract - Elizabeth Engle, PI
Aligned Reads
Individual gVCFs
Latest Release
May 28, 2019
First Release
Aug 23, 2018
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